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Oxcarbazepine Extended-Release Dosage

The amount of oxcarbazepine extended-release your healthcare provider prescribes will be determined based on how old you are, other medications you are taking, and other factors. This drug comes as a tablet that is taken once daily. The dosing guidelines call for oxcarbazepine extended-release to be used in combination with other anti-seizure medications and to be taken on an empty stomach.

An Introduction to Your Dosage of Oxcarbazepine Extended-Release

The dosage of oxcarbazepine extended-release (Oxtellar XR™) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your age
  • Your weight (in children)
  • How well your seizures are controlled
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Recommended Oxcarbazepine Extended-Release Dosing for Adults

The usual recommended initial dosage of oxcarbazepine extended-release for controlling partial seizures in adults is 600 mg a day. After 1 week, your healthcare provider may slowly increase your dose, as needed, by no more than 600 mg at a time. Your healthcare provider will wait at least a week between each dosage increase. 
Most people need to be treated with oxcarbazepine extended-release doses of 1200 mg to 2400 mg a day. While 2400 mg a day appeared to work better in clinical trials, this higher dosage was associated with more side effects.
People with severe kidney disease are usually started on oxcarbazepine extended-release 300 mg a day. The dosage may be increased slowly (no more often than once a week) by 300 mg to 450 mg, if necessary.
For older adults, the recommended oxcarbazepine extended-release starting dosage is 300 mg or 450 mg a day. The amount may be increased slowly (no more often than once a week) by 300 mg to 450 mg, if necessary.
If you are taking certain other anti-seizure medicines, such as carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®), phenobarbital (Luminal®), or phenytoin (Dilantin®, Phenytek®), your healthcare provider may start you on oxcarbazepine extended-release 900 mg a day, and slowly increase your dosage as needed from there. This is because certain other anti-seizure medicines can decrease blood levels of oxcarbazepine extended-release.
Oxcarbazepine extended-release contains the same active ingredient as Trileptal® (oxcarbazepine), but in a long-acting form. If your healthcare provider is converting you from Trileptal, you may need higher total daily doses of oxcarbazepine extended-release.
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Oxcarbazepine Extended-Release Information

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