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Bonine is a motion sickness medication that is available over the counter. It is approved to both treat and prevent symptoms of motion sickness; it comes in the form of a chewable tablet. Most people tolerate it well, but as with any medication, side effects are possible. Potential side effects of this medicine include dry mouth, drowsiness, and blurred vision.

What Is Bonine?

Bonine® (meclizine hydrochloride) is a non-prescription medication used to treat and prevent motion sickness symptoms. This article refers to Bonine Original chewable tablets; it does not apply to Bonine for Kids, which contains a different medication.
(Click Bonine Uses for more information, including possible off-label uses.)

Who Makes Bonine?

This medication is manufactured by Insight Pharmaceuticals.

How Does Bonine Work?

Bonine is part of a group of medications known as antihistamines, meaning that it blocks histamine receptors. However, it probably works for motion sickness by blocking acetylcholine receptors (by its "anticholinergic" activity), not by antihistamine activity.

When and How to Take It

General considerations include the following:
  • This medication comes in chewable tablet form. It is usually taken by mouth once a day or as directed by your healthcare provider.
  • You can take Bonine either with food or on an empty stomach. If the medication seems to bother your stomach, try taking it with a little food.
  • For the medication to work properly, it must be taken as directed.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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