Drug Interactions With Zonisamide (Cont.)

 
Phenytoin
Phenytoin can decrease the level of zonisamide in your blood, perhaps making it less effective. Your healthcare provider will likely recommend a higher zonisamide dosage if you are taking phenytoin, and may lower your dosage if you stop taking phenytoin.
 
Primidone
Taking zonisamide with primidone can decrease the level of zonisamide in your blood, perhaps making it less effective. Your healthcare provider will likely recommend a higher zonisamide dosage if you are taking primidone, and may lower your dosage if you stop taking primidone.
 

Drug Interactions With Zonisamide: Final Thoughts

It is possible that not all drug interactions with zonisamide were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;