• Zolmitriptan comes in regular tablets and as orally disintegrating tablets that dissolve in the mouth quickly. Zolmitriptan also comes in a nasal spray.
   
• Zolmitriptan should be taken as soon as possible once a migraine starts.
   
• Swallow Zolmitriptan tablets whole with a drink of water or other fluids. Zolmitriptan orally disintegrating tablets should be placed on the tongue, where they will be quickly dissolved. Zolmitriptan orally disintegrating tablets do not need to be taken with water.
   
• Each zolmitriptan nasal spray device contains only one dose of zolmitriptan. Spray the dose into one nostril while pressing on the other side of your nose, tilting your head back slightly and breathing in gently through your nose. After the spray, keep your head back and breathe gently through your mouth for about five seconds.
   
• If your headache comes back or does not go away, your healthcare provider may recommend taking a second dose of zolmitriptan after waiting at least two hours from the time you took the first dose. Let your healthcare provider know if zolmitriptan does not work completely after one dose.
   
• For zolmitriptan to work properly, it must be taken as prescribed. Zolmitriptan will not work if you stop taking it.
   

• How you respond to zolmitriptan
• Other medical conditions you may have
• Other medications you may be currently taking.