Drug Interactions With Trihexyphenidyl
Trihexyphenidyl Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when trihexyphenidyl is combined with any of the drugs listed above.
Acetylcholinesterase Inhibitor Medications
Taking trihexyphenidyl with an acetylcholinesterase inhibitor can make both medications less effective. Your healthcare provider may need to monitor you more closely and adjust your dose of these medications to prevent interactions from occurring.
Combining an anticholinergic medication with trihexyphenidyl (which is also an anticholinergic medication) can increase your risk of trihexyphenidyl side effects, such as dry mouth, constipation, dry eyes, or difficulty passing urine.
Both pramlintide and anticholinergic medications (including trihexyphenidyl) can slow down the movement of food through the digestive tract. Taking them together can increase the risk of constipation or nausea. Talk with your healthcare provider before combining these medications.
It is possible that not all trihexyphenidyl drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.