What Should I Tell My Healthcare Provider Before Taking Tiagabine?You should talk with your healthcare provider prior to taking this medication if you:
- Do not have seizures or epilepsy
- Have liver disease, including liver failure, hepatitis, or cirrhosis
- Have any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Gabitril and Pregnancy)
- Breastfeeding (see Gabitril and Breastfeeding).
Make sure to tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Tiagabine to learn more, including information on who should not take the drug.)
How Does It Work?Epilepsy is a brain disorder caused by recurring, brief changes in the brain's electrical system. These changes in brain activity can lead to a seizure (see Epilepsy Symptoms).
It is not known exactly how tiagabine works to prevent partial seizures in people with epilepsy. It may work by enhancing the effects of gamma-aminobutyric acid (GABA), a brain chemical that is naturally calming. GABA helps to slow down the brain's electrical system, thereby controlling seizures. Tiagabine also helps to keep GABA in the parts of the brain where it is active, preventing it from being removed and enhancing its effects.