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What Is Teriflunomide Used For?

How Does This Medicine Work?

It is not entirely clear how teriflunomide works to treat multiple sclerosis. What is known is that the drug blocks an enzyme in the body that is needed to make molecules known as pyrimidines. Lymphocytes (a white blood cell type that is involved in inflammation and active in MS) need pyrimidines to divide and reproduce. By preventing the body from making pyrimidines, teriflunomide reduces the number of lymphocytes in the body, which may be the reason it works to prevent MS relapses.

Can Children Use It?

Teriflunomide has not been approved for use in children, as it has not been adequately studied in this age group (usually defined as individuals younger than 18 years old). Talk to your child's healthcare provider about the risks and benefits of using teriflunomide in your child. 

Is It Safe for Older Adults to Use Teriflunomide?

This drug can be used in older adults. However, clinical studies of the drug did not include people over the age of 65 years old. Therefore, it is unknown whether older adults will respond to or tolerate the medication any differently than other age groups. For this reason, teriflunomide should probably be used cautiously in older adults.

What About Off-Label Uses?

On occasion, your healthcare provider may recommend this medicine for treating something other than multiple sclerosis. This is called an "off-label" use. At this time, there are no well-accepted off-label uses for teriflunomide.  
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Teriflunomide Drug Information

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