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Teriflunomide

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • High blood pressure (hypertension)
  • Bone marrow problems
  • A weakened immune system due to human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), or any other cause
  • Frequent or uncontrolled infections, or currently have an infection
  • Tuberculosis
  • Diabetes
  • Lung or breathing problems
  • Numbness or tingling in your hands or feet
  • Had serious skin reactions while using other medications
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 

Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Teriflunomide to learn more, including information on who should not take the drug.)
 

How Does It Work?

It is not entirely clear how teriflunomide works to treat multiple sclerosis. What is known is that the drug blocks an enzyme in the body that is needed to make molecules known as pyrimidines. Lymphocytes (a white blood cell type that is involved in inflammation and active in MS) need pyrimidines to divide and reproduce. By preventing the body from making pyrimidines, teriflunomide reduces the number of lymphocytes in the body, which may be the reason it works to prevent MS relapses.
 
Know the Signs - Concussion Safety

Teriflunomide Drug Information

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