Sydenham chorea is a childhood movement disorder characterized by rapid, irregular, aimless, involuntary movements of the muscles of the limbs, face, and trunk.
Sydenham chorea most often occurs in children between the ages of 5 and 15. It affects girls more often than boys.
Other names for Sydenham chorea include:
- St. Vitus dance
- Rheumatic chorea.
Causes of Sydenham Chorea
Sydenham chorea is considered to be a complication of acute rheumatic fever (streptococcal infection). In some cases, Sydenham chorea may be the only symptom a person with acute rheumatic fever experiences.
Sydenham chorea is believed to result from an autoimmune mechanism that occurs when the streptococcal infection causes the body to make antibodies to specific brain regions.
Symptoms of Sydenham Chorea
Sydenham chorea symptoms may appear gradually or suddenly. Common symptoms of Sydenham chorea can include:
- Rapid, irregular, aimless, involuntary movements of the muscles of the limbs, face, and trunk (known as chorea)
- Muscle weakness
- Hypotonia (decreased muscle tone)
- Clumsiness
- Emotional and behavioral problems, including obsessive-compulsive behavior.
The symptoms of Sydenham chorea vary in severity from mild cases -- in which there is restlessness, facial grimacing, and a slight degree of incoordination of movements -- to severe Sydenham chorea cases involving involuntary movements that incapacitate the child.
Sydenham chorea may strike up to six months after the fever or infection has cleared.
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