Drug Interactions With Sumatriptan

The following sections explain in detail the potentially negative interactions that can occur when sumatriptan is combined with any of the drugs listed above.

 

Taking sumatriptan with certain fibromyalgia or depression medications, including selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), can cause a group of symptoms called serotonin syndrome. These symptoms can include confusion, hallucinations, a fast heartbeat, feeling faint, fever, sweating, muscle spasms, difficulty walking, and diarrhea. Talk with your healthcare provider before taking these medications together. Also, you should call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.

 

Taking sumatriptan with ergot medications can increase your risk of dangerous side effects. Do not take sumatriptan and ergot medications within 24 hours of each other.

 

Taking sumatriptan with MAOIs can increase the amount of sumatriptan in your blood, perhaps increasing your chance of side effects. Do not take sumatriptan if you have used an MAOI within the last two weeks.

 

Taking sumatriptan with other triptans can increase your risk of serious side effects. These medications should not be taken within 24 hours of each other.

 

Drug Interactions With Sumatriptan: Summary

It is possible that not every sumatriptan drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific drug interactions with sumatriptan that may apply to you.