Drug Interactions With Sumatriptan
Interactions With Sumatriptan Explained
The following sections explain in detail the potentially negative interactions that can occur when sumatriptan is combined with any of the drugs listed above.
Taking sumatriptan with certain depression medications can cause a group of symptoms called serotonin syndrome. These symptoms include:
- Fast heartbeat
- Feeling faint
- Muscle spasm
- Difficulty walking
Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.
There are special warnings for MAOIs. Taking sumatriptan with a type A MAOI can greatly increase the amount of sumatriptan in your blood, increasing your chance of dangerous sumatriptan side effects. Do not take sumatriptan if you have used a type A MAOI within the last two weeks. Although selegiline and rasagiline are usually considered to be type B MAOIs, they may also be MAO-A inhibitors when used at high doses. Ask your healthcare provider before taking sumatriptan with selegiline or rasagiline.
Taking sumatriptan with ergot medications can increase your risk of dangerous side effects. Do not take sumatriptan and ergot medications within 24 hours of each other.
Taking sumatriptan with other triptans can increase your risk of serious side effects. These medications should not be taken within 24 hours of each other.