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Sumatriptan Transdermal

How Does It Work?

Sumatriptan transdermal belongs to a group of medicines known as serotonin (5-HT) agonists, more commonly known as "triptans." Migraine symptoms are thought to occur when blood vessels in the head widen and/or nerves in the head release certain substances that can trigger inflammation.
Like other triptans, sumatriptan transdermal works by binding to 5-HT receptors on these blood vessels and nerves. This causes the blood vessels to narrow and return to their normal state, and prevents the nerves from releasing the inflammation-causing substances. These actions are thought to help relieve migraine symptoms.

Clinical Effects for Sumatriptan Transdermal

In clinical studies, sumatriptan transdermal has been shown to help relieve migraine-related pain and other symptoms, such as nausea and sensitivity to sound and light. In one study, 18 percent of people who used sumatriptan transdermal to treat a migraine headache with moderate-to-severe pain were pain-free after two hours, while 53 percent reported their pain was less severe. In comparison, 9 percent of those who used a placebo (a patch with no active ingredient) were without pain after two hours, and 29 percent experienced a reduction in their pain.
In addition, more people who used sumatriptan transdermal reported relief of nausea and light and sound sensitivity after two hours.

When and How to Use This Patch

Some general considerations to keep in mind when using this patch include the following:
  • This medication comes in the form of a skin patch. It is applied directly on the skin as needed when a migraine occurs.
  • Sumatriptan transdermal should be applied to the upper arm or thigh only on a dry, hairless area of skin that is free from scars, tattoos, cuts, or irritation. You should only use one patch at a time.
  • The patches cannot be cut. They must be used whole.
  • Do not apply sumatriptan transdermal to a previously used area of your skin, unless that area has been free from redness for at least three days.
  • Once applied, you will need to activate the patch by pressing the activation button. Sumatriptan transdermal must be applied and activated within 15 minutes of assembly. 
  • Remove the patch four hours after you put it on, or when the red activation light turns off. The light will turn off when the complete dose has been delivered.
  • If your headache does not completely go away, or if it goes away but comes back, you may use another patch, as long as it been at least two hours since you activated the first one. Do not use more than two patches in a 24-hour period.
  • Do not swim, bathe, or shower while wearing sumatriptan transdermal because the patch contains batteries.
  • It is unknown if using more than four patches in one month is safe.
  • For the medication to work properly, it must be used as prescribed. Sumatriptan transdermal comes with instructions explaining exactly how to use it. Make sure to read and follow these instructions carefully.
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Sumatriptan Transdermal Information

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