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Side Effects of Rufinamide

Common Rufinamide Side Effects

Rufinamide has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking rufinamide in addition to their usual seizure medications were documented and compared to the side effects that occurred in another group of people taking their usual seizure medications plus a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it is possible to see what rufinamide side effects occurred, how often they appeared, and how they compared to the group taking the placebo.
Because rufinamide was added to other seizure medications and not used alone in clinical studies, the information from these studies probably does not accurately reflect the true incidence of side effects actually caused by rufinamide.
In these studies, the most common side effects of rufinamide (plus other seizure medications) included:
  • Headaches -- in up to 27 percent of people
  • Drowsiness -- up to 24.3 percent
  • Dizziness -- up to 19 percent
  • Vomiting -- up to 17 percent
  • Nausea -- up to 12 percent
  • Fatigue -- up to 9.5 percent
  • Double vision -- up to 9 percent.
Other common side effects, occurring in 3 to 8 percent of people, included:
  • The flu
  • Common cold symptoms
  • Decreased appetite
  • Rash
  • Coordination problems
  • Bronchitis
  • Sinus infections or irritation
  • Hyperactivity
  • Upper abdominal pain (stomach pain)
  • Ear infections
  • Attention problems
  • Itching
  • Shakiness (tremors)
  • Involuntary eye movements
  • Blurred vision
  • Constipation
  • Indigestion or heartburn
  • Back pain
  • A spinning sensation (vertigo)
  • Difficulty walking or changes in the walking pattern.
Know the Signs - Concussion Safety

Rufinamide Drug Information

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