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Rufinamide

What If I Take an Overdose?

It is not clear what exactly to expect from an overdose of this medication. If you happen to take too much rufinamide, seek immediate medical attention.
 
(Click Banzel Overdose for more information.)
 

What Should I Do If I Miss a Dose of Rufinamide?

If you forget to take your rufinamide dose, take the missed dose as soon as you remember. If it is almost time for your next dose, simply skip the missed dose and continue with your regular schedule. Do not take a double dose.
 

How Does It Work?

Seizures are the result of brief changes in how the brain's electrical system works. It is not known exactly how rufinamide works for treating seizures. Studies suggest that it may work by affecting sodium channels in the brain, preventing the abnormal activity from spreading to other parts. In particular, this medication seems to keep the sodium channels in an inactive state for a longer period of time, which helps control seizures.
 

Clinical Effects

This medication has been evaluated thoroughly in clinical studies. These studies evaluated rufinamide in people with Lennox-Gastaut syndrome whose seizures were not adequately controlled with their current medications. Adding rufinamide significantly reduced seizure frequency by 32.7 percent, compared to only 11.7 percent who were given a placebo (a "sugar pill" that does not contain any active ingredients) in addition to their regular seizure medications.
 
Know the Signs - Concussion Safety

Rufinamide Drug Information

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