Drug Interactions With Rasagiline

Numerous medications can potentially cause drug interactions with rasagiline, including certain antibiotics or antifungals, cough and cold or allergy products, and other monoamine oxidase inhibitors. These interactions could increase your risk of dangerous side effects or increase the level of rasagiline in your blood. Since drug interactions with rasagiline can be serious, check with your healthcare provider before taking any prescription or over-the-counter medication.

Drug Interactions With Rasagiline: An Overview

Rasagiline mesylate (Azilect®) can potentially interact with many medicines. Because so many drug interactions with rasagiline can be dangerous, it is important to check with your healthcare provider before taking any medication, whether prescription or over-the-counter. Make sure to tell all your healthcare providers (including dentists and surgeons) that you are taking rasagiline. Some of the medicines that may lead to drug interactions with rasagiline include:
 
 
    • Ciprofloxacin (Cipro®, Cipro® XR, Proquin® XR)
    • Ketoconazole (Nizoral®)
    • Norfloxacin (Noroxin®)
    • Ofloxacin (Floxin®)
    • Primaquine
    • Thiabendazole (Mintezol®)
 
  • Cough, cold, and allergy products, such as:
 
    • Dextromethorphan (Robitussin DM® and many others)
    • Naphazoline (various nasal and eyedrops, such as Visine-A®)
    • Oxymetazoline (various nasal and eyedrops, such as Afrin®)
    • Phenylephrine (Sudafed PE® and many others)
    • Propylhexedrine (Benzedrex®)
    • Pseudoephedrine (Sudafed® and many others)
 
 
 
  • Propoxyphene medications (Balacet™, Darvon®, Darvocet®)
  • "Pressor" medications, such as:
 
    • Dopamine
    • Ephedrine
    • Epinephrine (Adrenalin®, EpiPen®)
    • Isometheptene (Duradrin®, Midrin®, Migquin®, Migratine®, Migrazone®, Migrin-A®)
    • Levonordefrin (Carbocaine with Neo-Cobefrin®)
    • Midodrine (Orvaten®, ProAmatine®)
    • Norepinephrine (Levophed®)
 
 
 
  • Stimulants, such as:
 
 
 
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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