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Drug Interactions With Rasagiline

More Information on Interactions With Rasagiline

The following sections explain in detail the potentially negative interactions that can occur when rasagiline is combined with any of the drugs listed above.
 
Apraclonidine (Iopidine)
You should not use aproclonidine eye drops while taking rasagiline, due to the risk of dangerously high blood pressure (hypertension).
 
Atomoxetine (Strattera)
Atomoxetine and rasagiline should not be taken together or within two weeks of each other, due to the risk of dangerous side effects.
 
Brimonidine (Alphagan P, Combigan)
You should not use brimonidine eye drops while taking rasagiline, due to the risk of dangerously high blood pressure.
 
Buspirone (BuSpar)
You should not take buspirone while taking rasagiline (or even if you have taken rasagiline within the past 14 days), due to the risk of dangerously high blood pressure.
 
Certain Antibiotics, Antifungals, or Anti-Parasite Medications
Some antibiotics, antifungals, or anti-parasite medications can increase the level of rasagiline in your blood. A lower rasagiline dosage (0.5 mg once daily instead of the usual 1 mg once daily) may be recommended.
 
Cough, Cold, and Allergy Products
Taking rasagiline with many cough, cold, and allergy products, including eye drops or nasal products, can increase your risk of dangerous side effects, such as high blood pressure. Most of these products should never be taken with rasagiline. Always check with your healthcare provider before taking any cough, cold, or allergy products.
 
Cyclobenzaprine (Flexeril)
Do not take cyclobenzaprine and rasagiline within two weeks of each other, due to the risk of dangerous side effects, such as high blood pressure or seizures.
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