Nervous System Channel
Topics
Medications
Quicklinks
Related Channels

Drug Interactions With Phenytoin

Digoxin 
Phenytoin may make digoxin less effective. If you are taking these drugs together, your healthcare provider may need to increase your digoxin dosage.
 
Disulfiram 
Disulfiram can raise the amount of phenytoin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of phenytoin in your blood and adjust your dose as necessary.
 
Doxycycline
Phenytoin may make doxycycline less effective. If you are taking these drugs together, your healthcare provider may need to increase your doxycycline dosage.
 
Estrogen Medications
Estrogens can raise the amount of phenytoin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of phenytoin in your blood and adjust your dose as necessary. Also, phenytoin can make estrogens less effective, which is especially important for estrogens in oral contraceptives (birth control pills).
 
Folic Acid
Folic acid may decrease the level of phenytoin in your blood. Check with your healthcare provider before combining these products.
 
Fluoxetine
Fluoxetine can raise the amount of phenytoin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of phenytoin in your blood and adjust your dose as necessary.
 
Fluvastatin
Fluvastatin can raise the amount of phenytoin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of phenytoin in your blood and adjust your dose as necessary. In addition, phenytoin may decrease fluvastatin levels, perhaps making it less effective.
 
Fluvoxamine
Fluvoxamine can raise the amount of phenytoin in your blood, increasing your risk of side effects. Your healthcare provider may need to measure the level of phenytoin in your blood and adjust your dose as necessary.
Know the Signs - Concussion Safety

Phenytoin Sodium

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.