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What Is Perampanel Used For?

If you have partial-onset seizures, you may be able to reduce their frequency by using perampanel. This prescription medication works to control seizures by preventing the spread of abnormal activity in the brain. It is approved for adults and adolescents age 12 and older. Perampanel is meant to be used in combination with other anti-seizure medications.

An Overview of Uses for Perampanel

Perampanel (Fycompa™) is a prescription medication approved to treat a certain type of seizure known as partial-onset seizure in people with epilepsy who are at least 12 years old. It belongs to a group of medicines known as anti-epileptic drugs, or simply anti-seizure medications. Perampanel is only approved for use in combination with other anti-seizure medicines.

Understanding Epilepsy

Epilepsy is a medical condition in which a person has recurrent seizures. Seizures result from episodes of brief, abnormal electrical activity in the brain. There are many different types of seizures, which can generally be categorized into one of two groups, based on how they start: partial-onset seizures and generalized seizures (see Types of Seizures for more information).
Generalized seizures affect the entire brain. Depending on the specific type, generalized seizures can cause abnormal body movements, convulsions, loss of consciousness, or brief periods of fixed staring.
Partial-onset seizures, also called focal seizures, begin in one area of the brain. There are two main types: simple partial seizures and complex partial seizures. Simple partial seizures do not alter consciousness, and people remain aware of the events around the time of the seizure. Complex partial seizures, on the other hand, affect consciousness, and cause a person to lose awareness of what is happening.
In some cases, a partial-onset seizure can spread throughout the brain and become generalized. This is known as a partial-onset seizure with secondary generalization.
Perampanel is approved to treat partial-onset seizures with or without secondary generalized seizures. It is not a cure for epilepsy, but can help reduce the frequency of seizures. As mentioned, this medication is only approved for treatment when used with other anti-seizure medicines. This is because, at this time, it has not been adequately studied for use alone. In clinical trials, people were taking at least one to three other anti-seizure medicines in addition to perampanel.
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Perampanel Medication Information

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