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Parlodel Drug Interactions

Parlodel Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Parlodel is combined with any of the drugs listed above.
Combining Parlodel with an antipsychotic medication could make both medications less effective (since they work in opposite ways). In general, Parlodel should not be used in combination with an antipsychotic medication.
Certain Antibiotics
Taking Parlodel with certain antibiotics can increase the risk of certain problems (including pain, cramping, and decreased blood flow to the extremities). These problems can be quite serious. Do not take these medications together without your healthcare provider's approval and supervision.
Certain Antidepressants
Taking Parlodel with certain depression medications can cause a group of symptoms called serotonin syndrome.
These symptoms include:
  • Confusion
  • Hallucination
  • Fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasm
  • Difficulty walking
  • Diarrhea.


Talk to your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.

Ergot Medications
Taking Parlodel with other ergot medications can cause serotonin syndrome. Talk to your healthcare provider before taking these medications together. It is not recommended to take Parlodel in combination with any other ergot medications.
Metoclopramide (Reglan)
Metoclopramide can make Parlodel less effective. Check with your healthcare provider before taking these two medications together.
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Parlodel Drug Information

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