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What Is Oxcarbazepine Extended-Release Used For?

How Does This Medicine Work?

Seizures are the result of brief abnormal activity in the brain's electrical system. It is unknown exactly how oxcarbazepine extended-release works for treating seizures. Studies suggest that it may work by blocking brain sodium channels that are sensitive to electrical changes in the brain. By blocking sodium channels in the brain, oxcarbazepine extended-release helps stabilize neurons and prevents them from firing rapidly. This helps prevent the spread of abnormal electrical activity to other areas of the brain.
Oxcarbazepine extended-release contains the extended-release, once-daily form of oxcarbazepine. Regular release oxcarbazepine is the active ingredient in another anti-seizure medication known as Trileptal®.

Can Children Use It?

Oxcarbazepine extended-release is approved for use in children age six and older. It is not approved for use in children younger than age six because the size of the tablets is not appropriate for younger children (and the tablets must be swallowed whole). This medication has not been adequately studied in children younger than four years old. Talk to your child's healthcare provider about the risks and benefits of using this medication in children.

Is It Safe for Older Adults to Use Oxcarbazepine Extended-Release?

In clinical studies, adults older than age 60 years had higher blood levels of the medication compared to younger individuals. It is recommended that older adults be started on lower oxcarbazepine extended-release doses (300 mg or 450 mg a day). This dose can be slowly increased, no more often than once a week, if necessary to effectively control seizures.

What About Off-Label Uses?

On occasion, your healthcare provider may recommend this medicine for treating something other than partial seizures. This is called an "off-label" use. Oxcarbazepine extended-release may be used for a variety of off-label reasons, including the treatment of:
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Oxcarbazepine Extended-Release Information

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