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Side Effects of Orally Disintegrating Selegiline

Some of the most common side effects of orally disintegrating selegiline include nausea, dizziness, and headaches. Although many people tolerate the medication fairly well, serious side effects are possible. Make sure to notify your healthcare provider right away if you develop any serious orally disintegrating selegiline side effects, such as hallucinations, depression, or allergic reactions.

An Introduction to Side Effects of Orally Disintegrating Selegiline

As with any medicine, side effects are possible with orally disintegrating selegiline (Zelapar®). However, not everyone who takes the drug will experience side effects. Many people tolerate it quite well. If side effects do occur, they are often minor and either require no treatment or are easily treated by you or your healthcare provider. However, serious side effects of orally disintegrating selegiline are also possible.
(This article covers many, but not all, of the possible side effects with orally disintegrating selegiline. Your healthcare provider can discuss a more complete list of orally disintegrating selegiline side effects with you.)

Serious Side Effects of Orally Disintegrating Selegiline

Orally disintegrating selegiline has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and compared to the side effects that occurred in another group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine.
Some side effects with orally disintegrating selegiline are potentially serious and should be reported immediately to your healthcare provider. Although most of these serious side effects are rare, a few may be common. Serious side effects of the drug include but are not limited to:
    • Headaches
    • Feelings of a rapidly or forcefully beating heart (palpitations)
    • A sore or stiff neck
    • Nausea or vomiting
    • Sweating, with a high fever (or sometimes with cold, clammy skin)
    • Sensitivity to light
    • A rapid heart rate (tachycardia) or low heart rate (bradycardia)
    • Chest pain or throat tightness
    • Dilated (wide open) pupils
    • Dizziness
    • Lightheadedness
    • Fainting
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
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