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Drug Interactions With Orally Disintegrating Selegiline

Orally Disintegrating Selegiline Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when orally disintegrating selegiline is combined with any of the drugs listed above.
 
Apraclonidine (Iopidine)
You should not use apraclonidine eyedrops while taking orally disintegrating selegiline, due to the risk of dangerously high blood pressure (hypertension).
 
Atomoxetine (Strattera)
Strattera and orally disintegrating selegiline should not be taken together or within two weeks of each other, due to the risk of dangerous side effects.
 
Brimonidine (Alphagan P, Combigan)
You should not use brimonidine eyedrops while taking orally disintegrating selegiline, due to the risk of dangerously high blood pressure.
 
Buspirone (BuSpar)
You should not take buspirone while taking orally disintegrating selegiline (or even if you have taken orally disintegrating selegiline within the past 14 days), due to the risk of dangerously high blood pressure.
 
Cough, Cold, and Allergy Products
Taking orally disintegrating selegiline with many cough, cold, and allergy products (including eyedrops or nasal products) can increase your risk of dangerous side effects, such as high blood pressure. Most of these products should never be taken with orally disintegrating selegiline. Always check with your healthcare provider before taking any cough, cold, or allergy products.
 
Cyclobenzaprine (Flexeril)
Do not take cyclobenzaprine and orally disintegrating selegiline within two weeks of each other, due to the risk of dangerous side effects, such as high blood pressure or seizures.
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