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Orally Disintegrating Carbidopa-Levodopa

How Should Orally Disintegrating Carbidopa-Levodopa Be Stored?

Orally disintegrating carbidopa-levodopa tablets should be stored at room temperature, away from moisture, heat, and light. Keep orally disintegrating carbidopa-levodopa and all other medications out of the reach of children.

What Should I Do If I Miss a Dose of Orally Disintegrating Carbidopa-Levodopa?

If you forget to take a dose of orally disintegrating carbidopa-levodopa, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose of the medication.

How Does Orally Disintegrating Carbidopa-Levodopa Work?

A deficiency of dopamine (caused by a loss of dopamine-producing cells) in certain parts of the brain may be responsible for many of the symptoms of Parkinson's disease. Although it would make sense to give dopamine itself to help treat Parkinson's, this does not work, as dopamine cannot cross the blood-brain barrier to reach the brain. Levodopa is a precursor of dopamine, which means that the body can use levodopa to make dopamine. Unlike dopamine, levodopa crosses the blood-brain barrier.
Levodopa is almost always given in combination with carbidopa. Carbidopa delays the conversion of levodopa into dopamine until it reaches the brain, preventing or diminishing some of the side effects (especially nausea and vomiting) that often accompany levodopa therapy. Carbidopa also reduces the amount of levodopa needed for Parkinson's disease treatment.
Because orally disintegrating carbidopa-levodopa tablets are designed to dissolve rapidly on the tongue, they can be especially useful for people who have difficulty swallowing, a problem common in people with Parkinson's disease.
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