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Drug Interactions With Orally Disintegrating Carbidopa-Levodopa

Orally Disintegrating Carbidopa-Levodopa Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when orally disintegrating carbidopa-levodopa is combined with any of the drugs listed above.
 
Antipsychotic Medications
Antipsychotic medications may decrease the effectiveness of orally disintegrating carbidopa-levodopa. Check with your healthcare provider before taking these medications together.
 
Blood Pressure Medications
Taking orally disintegrating carbidopa-levodopa and a high blood pressure medication together can increase the risk of low blood pressure (known medically as hypotension). Your healthcare provider may need to monitor your blood pressure more closely, and you may need a lower dose of your blood pressure medication.
 
Iron Products
Iron can decrease the absorption of orally disintegrating carbidopa-levodopa into the body, perhaps making it less effective. Iron products should be taken at least two hours before or after any dose of orally disintegrating carbidopa-levodopa.
 
Isoniazid
Isoniazid can make orally disintegrating carbidopa-levodopa less effective. Check with your healthcare provider before taking these medications together.
 
Metoclopramide (Reglan)
Metoclopramide can make orally disintegrating carbidopa-levodopa less effective. However, metoclopramide may also increase the absorption of orally disintegrating carbidopa-levodopa into the body (which could make it more effective or increase the risk of side effects). It is difficult to predict what exactly may happen if these medications are combined. Check with your healthcare provider before taking these medications together.
The Dirty, Messy Part of BPH

Info on Orally Disintegrating Carbidopa-Levodopa

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