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Nuedexta Drug Interactions

Fesoterodine
Combining Nuedexta with fesoterodine may increase the amount of fesoterodine in your body, increasing your risk for side effects. It general, people who take Nuedexta should not take more than 4 mg of fesoterodine. Talk to your healthcare provider about this potential interaction, as you may need a lower fesoterodine dose.
 
Guanfacine
Nuedexta may increase the levels of guanfacine in your blood, increasing your risk for side effects, such as low blood pressure and a slow heart rate. Your healthcare provider may choose to monitor you more closely if you take these medications together.
 
Hydrocodone
Nuedexta can make hydrocodone less effective at controlling pain. Your healthcare provider may choose to monitor your pain level more closely if you take these medications together to make sure hydrocodone is working for you.
 
Linezolid
Linezolid is an antibiotic that has monoamine oxidase inhibitor (MAOI) properties. Because Nuedexta should not be taken within two weeks of an MAOI, it is important for people who take (or have recently taken) linezolid to not use Nuedexta.
 
Lurasidone
Combining Nuedexta with lurasidone may increase the level of lurasidone in your blood, increasing your risk for potentially serious side effects. In general, these medications should not be taken together.
 
Malaria Medications
Taking Nuedexta with antimalarial medications increases the risk of QT prolongation, a dangerous type of arrhythmia. Talk to your healthcare provider about this possible interaction before taking these medications together. In general, Nuedexta should not be taken with quinidine, quinine, or mefloquine.
 
Maraviroc
Nuedexta may increase the level of maraviroc in your body, increasing your risk for side effects. Your healthcare provider may choose to lower your maraviroc dose. People with severe kidney disease should not take maraviroc with Nuedexta.
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Nuedexta Medication Information

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