Divalproex ER (Depakote ER^®) is a medication that is licensed for preventing migraine headaches and for treating mania and epilepsy. It is approved for treating mania only in adults, but can be used for both migraine prevention and epilepsy treatment in children.

This medication is the long-acting form of divalproex; it only needs to be taken once a day. Do not crush, break, or chew divalproex ER, as it is an extended-release tablet. Although most people are able to use it without any problems, divalproex ER has the potential to cause a number of side effects, such as nausea, indigestion, and drowsiness.

(To learn more about taking this extended-release product, click Divalproex ER. This article has details on the different strengths available, what to do if you are pregnant or breastfeeding, drug warnings, and more.)

Divalproex Extended Release

Written by/reviewed by: Arthur Schoenstadt, MD

Last reviewed by: Arthur Schoenstadt, MD

Divalproex ER

Side Effects of Divalproex ER

What Is Divalproex ER Used For?

Divalproex ER Dosing

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Precautions and Warnings With Divalproex ER

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