Apomorphine Hydrochloride Drug Info

Apomorphine hydrochloride (Apokyn^®) is a drug that works by increasing the levels of dopamine in the brain. It is used to treat "off" episodes of Parkinson's disease. Nausea, vomiting, and drowsiness are some of the most common side effects. Because of the potential for side effects, a nausea/vomiting medication known as trimethobenzamide (Tigan^®) must be started three days before you take your first dose of apomorphine.

 

Before beginning treatment with this drug, information on apomorphine hydrochloride's risks should be fully reviewed with your healthcare provider. Tell him or her if you have any other medical conditions or are taking any other drugs, including prescription and nonprescription medicines, vitamins, and herbal supplements.

 

When you are first starting apomorphine, your healthcare provider will administer a "test dose" and closely monitor how you respond. Your blood pressure will be monitored for at least an hour afterward. If you tolerate the test dose well, your starting dosage should be 0.2 mL injected under the skin as necessary, up to five times a day