Drug Interactions With Naratriptan (Cont.)

Naratriptan Interactions Explained

 
Certain Antidepressants
Talk to your healthcare provider before taking naratriptan with an antidepressant. Taking naratriptan with certain depression medications, including selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), can cause a group of symptoms called serotonin syndrome. These symptoms include:
 
  • Hallucinations
  • Confusion
  • Diarrhea
  • A fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasms
  • Difficulty walking.
 
Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.
 
Ergot Medications
Taking naratriptan with ergot medications can increase your risk of dangerous side effects. Do not take naratriptan and ergot medications within 24 hours of each other.
 
Triptans
Taking naratriptan with other triptans can increase your risk of serious side effects. These medications should not be taken within 24 hours of each other.
 

Final Thoughts on Drug Interactions With Naratriptan

It is possible that not every naratriptan drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific drug interactions with naratriptan that may apply to you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;