Mysoline Drug Interactions

Alcohol, antidepressants, and sleep medications are some of the drugs that can interact with Mysoline. Some of these Mysoline drug interactions can alter the amounts of the medications in your blood, potentially increasing your risk of side effects (such as confusion and difficulty breathing) or decreasing the effectiveness of the drugs.

 

An Overview of Mysoline Drug Interactions

Mysoline® (primidone) can potentially interact with other medications. Some of these medicines that may lead to Mysoline interactions include:
 
  • Alcohol
  • Anesthetics
  • Antidepressant medications
  • Barbiturates, such as:
o Amobarbital (Amytal®)
o Butalbital (Fioricet®, Fiorinal®)
o Pentobarbital (Nembutal®)
o Phenobarbital (Luminal®)
o Secobarbital (Seconal®) 
  • Benzodiazepines, including:
o Lorazepam (Xanax®, Xanax® XR)
  • Certain antifungal medications, including:
o Fluconazole (Diflucan®)
o Itraconazole (Sporanox®)
o Ketoconazole (Nizoral®)
o Voriconazole (Vfend®) 
  • HIV or AIDS medications
  • Hormonal contraceptives, including birth control pills, patches, rings, and implants
  • Narcotics or opiates, such as morphine, oxycodone (OxyContin®), or hydrocodone (Lortab®, Vicodin®)
  • Other seizure medications
  • Sleep medications.
     
(Mysoline Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;