Mysoline Drug Interactions

Alcohol, antidepressants, and sleep medications are some of the drugs that can interact with Mysoline. Some of these Mysoline drug interactions can alter the amounts of the medications in your blood, potentially increasing your risk of side effects (such as confusion and difficulty breathing) or decreasing the effectiveness of the drugs.

An Overview of Mysoline Drug Interactions

Mysoline® (primidone) can potentially interact with other medications. Some of these medicines that may lead to Mysoline interactions include:
 
  • Alcohol
  • Anesthetics
  • Antidepressant medications
  • Barbiturates, such as:
o Amobarbital (Amytal®)
o Butalbital (Fioricet®, Fiorinal®)
o Pentobarbital (Nembutal®)
o Phenobarbital (Luminal®)
o Secobarbital (Seconal®) 
  • Benzodiazepines, including:
o Lorazepam (Xanax®, Xanax® XR)
  • Certain antifungal medications, including:
o Itraconazole (Sporanox®)
o Ketoconazole (Nizoral®)
o Voriconazole (Vfend®) 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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