Mysoline Dosage

When determining a patient's Mysoline dosage, a healthcare provider will consider several factors, such as the patient's age. Mysoline comes in the form of a tablet and is generally taken one to three times a day. In general, a healthcare provider will likely recommend a lower Mysoline dose, and then slowly increase the dosage until the seizures are under control.

 

Mysoline Dosage: An Introduction

The dose of Mysoline® (primidone) that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Your age
  • Other medications you may be taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your Mysoline dose unless your healthcare provider specifically instructs you to do so.
 

Mysoline Dosing for Adults and Older Children

For adults and children eight years old and older, your healthcare provider will likely recommend that you start with a low Mysoline dose and slowly increase your dose as follows:
 
  • Days 1 to 3 -- Mysoline 100 mg or 125 mg at bedtime
  • Days 4 to 6 -- Mysoline 100 mg or 125 mg twice daily
  • Days 7 to 9 -- Mysoline 100 mg or 125 mg three times daily
  • Day 10 and beyond -- Mysoline 250 mg three times daily.
     
If necessary, your healthcare provider may increase your dose further in order to control your seizures. In general, you should not take more than 2000 mg of Mysoline per day.
 

Mysoline Dosing for Children

For children under eight years old, the following Mysoline dose is usually recommended:
 
  • Days 1 to 3 -- Mysoline 50 mg at bedtime
  • Days 4 to 6 -- Mysoline 50 mg twice daily
  • Days 7 to 9 -- Mysoline 100 mg twice daily
  • Day 10 and beyond -- Mysoline 125 mg to 250 mg three times daily.
     
(Mysoline Dosage Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;