Nervous System Channel
Topics
Medications
Quicklinks
Related Channels

Machado-Joseph Disease

Treatment Options

Machado-Joseph disease is incurable, but some of its symptoms can be treated. Treatment can include the following:
 
  • Levodopa therapy can help for many years for those patients who show Parkinson's features.
 
  • Antispasmodic drugs, such as baclofen, can help reduce spasticity.
 
  • Botulinum toxin can treat severe spasticity as well as some symptoms of dystonia. However, botulinum toxin should be used as a last resort due to the possibility of side effects such as swallowing problems (dysphagia).
 
  • Medication and speech therapy can be used to treat patients with speech problems (dysarthria) and dysphagia.
 
  • Wearing prism glasses can reduce blurred or double vision, but eye surgery has only short-term benefits due to the progressive degeneration of eye muscles.
 
  • Physiotherapy can help patients cope with disability associated with gait problems, and physical aids, such as walkers and wheelchairs, can assist the patient with everyday activities.
 
  • Medications and medical care can be used to treat other Machado-Joseph disease problems such as sleep disturbances, cramps, and urinary dysfunction.
 

Prognosis for Machado-Joseph Disease

Machado-Joseph disease is also a progressive disease, meaning that symptoms will get worse with time. Life expectancy ranges from the mid-thirties for those with severe forms of the disease to a normal life expectancy for those with mild forms of the disease. An early death from Machado-Joseph disease is usually caused by aspiration pneumonia.
Know the Signs - Concussion Safety
Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.