Nervous System Home > Drug Interactions With Trihexyphenidyl

Certain medications can cause drug interactions with trihexyphenidyl, including pramlintide, anticholinergic drugs, and acetylcholinesterase inhibitors. Some interactions will decrease the effectiveness of the medicines, while others can increase your risk of developing side effects (such as constipation, nausea, dry mouth, dry eyes, or difficulty passing urine). Make sure to talk to your healthcare provider about any specific trihexyphenidyl drug interactions that may apply to you.

Trihexyphenidyl Drug Interactions: An Overview

Trihexyphenidyl hydrochloride (Artane®) can potentially interact with several different medications. Some of the medicines that may lead to trihexyphenidyl drug interactions include:
  • Acetylcholinesterase inhibitor medications, including:



  • Anticholinergic drugs, such as:



Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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