) is a prescription medication used to treat Parkinson's disease
. It is always used in combination with carbidopa-levodopa
, Sinemet CR
, or Parcopa®
), as it is not effective at treating Parkinson's disease without the use of levodopa. Tolcapone is useful for people who experience otherwise uncontrollable fluctuations in their symptoms, such as "wearing off" of their carbidopa
-levodopa before each dose.
Due to the risk of potentially fatal liver failure that is sometimes caused by tolcapone, people should only use this drug if other alternatives are not acceptable or do not work.
Side Effects of Tolcapone
Tolcapone is never used without carbidopa-levodopa, as it is not effective at treating Parkinson's disease without levodopa.
Common side effects of tolcapone (when combined with carbidopa-levodopa) include but are not limited to:
- Involuntary movements (dyskinesia)
- Sleeping problems (such as insomnia)
- Uncontrollable, sustained muscle contractions (dystonia).
(Click Side Effects of Tolcapone to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)