Sumatriptan is licensed to relieve symptoms of migraine headaches. It works by causing the blood vessels in the head to return to their normal state after dilating during a migraine. Conditions you should let your healthcare provider know about before taking the drug include heart problems, high blood pressure, and a history of seizures. Side effects include tingling sensations, dizziness, and chest discomfort.
Brand-name Imitrex is made by GlaxoSmithKline. Sumavel is made by Patheon UK, Ltd., for Zogenix, Inc. Alsuma is made by Meridian Medical Technologies™, Inc. Zecuity is manufactured by NuPathe, Inc.
How Does It Work?
Sumatriptan is part of a class of migraine medications called 5-HT agonists (more commonly known as "triptans"). During a migraine headache, some of the blood vessels in the head can become dilated (wider than they usually are). Sumatriptan works by narrowing these blood vessels, helping them return to their normal state. This action helps to relieve migraine symptoms.
Sumavel [package insert]. San Diego, CA: Zogenix, Inc.;2009 July.
Imitrex Tablets [package insert]. Research Triangle Park, NC: GlaxoSmithKline;2007 April.
Imitrex Injection [package insert]. Research Triangle Park, NC: GlaxoSmithKline;2007 April.
Imitrex Nasal Spray [package insert]. Research Triangle Park, NC: GlaxoSmithKline;2007 April.
Alsuma [package insert]. Columbia, MD: Meridian Medical Technologies, Inc.;2010 June.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed February 13, 2009.
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