Nervous System Home > Sumatriptan Dosing

The usual dose of sumatriptan tablets for the treatment of migraine headaches is 25 mg, 50 mg, or 100 mg. For those using the nasal spray, the sumatriptan dosage is 5 mg, 10 mg, or 20 mg sprayed into one nostril. If you are receiving sumatriptan through an injection, the usual dosage is 4 mg or 6 mg injected subcutaneously (just below the skin). Among the factors that can affect sumatriptan dosing are other drugs you may be currently taking, other medical conditions you may have, and your response to sumatriptan.

An Overview of Sumatriptan Dosing

The dose of sumatriptan succinate (Alsuma™, Imitrex®, Sumavel®, Zecuity™) your healthcare provider prescribes will vary depending on a number of factors, including:
  • Your response to sumatriptan
  • Other medical conditions you may have
  • Other medications you may be currently taking.
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Sumatriptan Dosage for Migraine or Cluster Headaches

Sumatriptan is meant to be taken only during a migraine or cluster headache. The usual dosages of sumatriptan for migraine are:
  • Sumatriptan tablets -- 25 mg, 50 mg, or 100 mg by mouth.


  • Sumatriptan nasal spray -- 5 mg, 10 mg, or 20 mg sprayed into one nostril. Since sumatriptan nasal spray does not come in a 10 mg strength, use two of the 5 mg sprays (one in each nostril) to get a 10 mg dose.


  • Sumatriptan injection -- 4 mg or 6 mg injected subcutaneously (just below the skin).
  • Sumatriptan patch -- 1 patch applied to the skin, which delivers 6.5 mg of sumatriptan over 4 hours.


The usual dose for treating cluster headaches is 4 mg or 6 mg injected subcutaneously. The tablet and nasal spray forms of sumatriptan are not approved for cluster headache treatment.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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