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Adults and adolescents who have partial-onset seizures may receive an anti-seizure drug called perampanel. This prescription medicine comes as a tablet that is taken once daily at bedtime. It works by preventing the spread of abnormal activity in the brain. People who have depression, liver disease, or certain other medical conditions may not be able to safely use this drug.

 

What Is Perampanel?

Perampanel (Fycompa™) is a prescription anti-seizure medication. It is approved for use with other anti-seizure medicines to treat partial-onset seizures in adults and children as young as 12 years old with epilepsy.
 
Partial seizures are a type of seizure that occurs in just one area of the brain. In some cases, partial seizures can spread and turn into seizures that affect the entire brain. This is known as "secondary generalization." Perampanel is approved to treat partial-onset seizures that remain in one area of the brain and partial-onset seizures with secondary generalization.
 
(Click What Is Perampanel Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, perampanel can cause side effects. However, not everyone who takes the drug will experience problems. Most people tolerate it quite well.
 
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
 
Common side effects of perampanel include but are not limited to:
 
  • Dizziness
  • Sleepiness
  • Fatigue
  • Irritability.
 
(Click Perampanel Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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