Nervous System Home > Parlodel Warnings and Precautions

Be sure to tell your healthcare provider if you have liver disease, heart disease, or kidney disease before taking Parlodel. Warnings and precautions also include watching out for potential drug interactions and avoiding the medication altogether if you have uncontrolled high blood pressure, are allergic to ergot alkaloids, or are allergic to any components used to make Parlodel.

Parlodel: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Parlodel® (bromocriptine mesylate) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings for Parlodel

Warnings and precautions to be aware of prior to taking Parlodel include the following:
  • Parlodel has been reported to cause heart attacks, strokes, high blood pressure (hypertension), and low blood pressure (hypotension).
  • At one point, Parlodel was approved to suppress postpartum lactation (to suppress breast milk production after childbirth for women who will not be breastfeeding). However, Parlodel is no longer approved for this use, since the benefits of Parlodel are not worth the risk of serious side effects (such as strokes) for this use (see Parlodel and Breastfeeding).
  • There have been some cases of lung problems in people who took Parlodel. In general, these problems slowly improved after Parlodel was stopped.


  • Intense, unusual urges have been reported in people taking Parkinson's disease medications. Examples include an intense desire to gamble or to engage in risky sexual behavior. Let your healthcare provider know right away if you experience any of these urges.
  • People with Parkinson's disease have an increased risk for melanoma (a type of skin cancer). At this time, it is not clear if this is caused by Parkinson's disease medications or other factors. It is a good idea to have regular skin checks to monitor for this problem. 


  • It is not known whether Parlodel is safe for people with liver or kidney disease.
  • Parlodel can worsen psychosis and heart disease. If you have a history of such problems, Parlodel may not be a good choice for you.
  • Let your healthcare provider know if you develop blue, numb fingers or toes while taking Parlodel. Your Parlodel dosage may need to be reduced. Keeping your fingers and toes warm can help prevent this problem.
  • Parlodel can cause hallucinations (seeing, hearing, or feeling things that are not really there) or other psychological problems. Let your healthcare provider know if you develop hallucinations while taking Parlodel.
  • Parlodel can potentially interact with several medications (see Parlodel Drug Interactions).
  • Parlodel is usually considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the benefits may not outweigh the risks in many cases (see Parlodel and Pregnancy).
  • Women should not take Parlodel while breastfeeding. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Parlodel and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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