Nervous System Home > Oxcarbazepine Extended-Release Side Effects

Some of the possible side effects of oxcarbazepine extended-release can include headaches, double vision, and balance problems. Studies have shown that most people who use this drug tolerate it well, and most reactions are generally easy to treat. However, because oxcarbazepine extended-release is associated with potentially serious reactions, such as dangerous infections, let your healthcare provider know immediately if you develop something that doesn't seem right.

An Introduction to Side Effects of Oxcarbazepine Extended-Release

As with any medicine, oxcarbazepine extended-release (Oxtellar XR™) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with oxcarbazepine extended-release. Your healthcare provider can discuss a more complete list with you.)

Serious Oxcarbazepine Extended-Release Side Effects

Some oxcarbazepine extended-release side effects are potentially serious and should be reported to your healthcare provider immediately. These potential reactions include but are not limited to:
  • Signs of low blood sodium levels (hyponatremia), such as:
    • Loss of appetite
    • Nausea
    • Tiredness or low energy
    • Headache
    • Confusion
    • Irritability
    • Muscle weakness
    • Muscle cramps or spasms
  • More frequent or more severe seizures
  • Behaviors or thoughts around suicide or harming yourself (see Seizure Medications and Suicide)
  • Depression that is new or worse
  • Any unusual changes in your mood, thoughts, or behavior
  • A skin rash of any kind, as this medication can cause life-threatening skin reactions
  • Signs of infection, such as:
    • Fever
    • Aches and pains
    • Chills
    • Swollen glands
    • A sore throat
  • Recurring infections or infections that do not improve
  • Signs of anemia, such as:
    • Weakness
    • Fatigue
    • Shortness of breath
    • Pale skin
  • Unusual bleeding or bruising
  • Painful sores in the mouth or around the eyes
  • Yellowing of the skin or whites of the eyes (jaundice)
  • Abdominal (stomach) pain
  • Changes in how much you urinate
  • Dark urine
  • Severe muscle or joint pain
  • Confusion
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching, flaking, or peeling of the skin
    • Unexplained swelling, especially of the face, lips, or throat
    • Difficulty swallowing or breathing.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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