Nervous System Home > Oxcarbazepine Extended-Release Dosage
The amount of oxcarbazepine extended-release your healthcare provider prescribes will be determined based on how old you are, other medications you are taking, and other factors. This drug comes as a tablet that is taken once daily. The dosing guidelines call for oxcarbazepine extended-release to be used in combination with other anti-seizure medications and to be taken on an empty stomach.
The dosage of oxcarbazepine extended-release (Oxtellar XR™) your healthcare provider recommends will vary, depending on a number of factors, including:
- Your age
- Your weight (in children)
- How well your seizures are controlled
- Other medications you are taking
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
The usual recommended initial dosage of oxcarbazepine extended-release for controlling partial seizures in adults is 600 mg a day. After 1 week, your healthcare provider may slowly increase your dose, as needed, by no more than 600 mg at a time. Your healthcare provider will wait at least a week between each dosage increase.
Most people need to be treated with oxcarbazepine extended-release doses of 1200 mg to 2400 mg a day. While 2400 mg a day appeared to work better in clinical trials, this higher dosage was associated with more side effects.
People with severe kidney disease are usually started on oxcarbazepine extended-release 300 mg a day. The dosage may be increased slowly (no more often than once a week) by 300 mg to 450 mg, if necessary.
For older adults, the recommended oxcarbazepine extended-release starting dosage is 300 mg or 450 mg a day. The amount may be increased slowly (no more often than once a week) by 300 mg to 450 mg, if necessary.
If you are taking certain other anti-seizure medicines, such as carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®), phenobarbital (Luminal®), or phenytoin (Dilantin®, Phenytek®), your healthcare provider may start you on oxcarbazepine extended-release 900 mg a day, and slowly increase your dosage as needed from there. This is because certain other anti-seizure medicines can decrease blood levels of oxcarbazepine extended-release.
Oxcarbazepine extended-release contains the same active ingredient as Trileptal® (oxcarbazepine), but in a long-acting form. If your healthcare provider is converting you from Trileptal, you may need higher total daily doses of oxcarbazepine extended-release.