Nervous System Home > Orap Side Effects
Your healthcare provider needs to know right away if you develop serious problems like seizures, confusion, or difficulty breathing while taking Orap. Although not everyone who takes this medication experiences problems, some of the commonly reported side effects of Orap include drowsiness, vision problems, and abnormal behaviors. Seek medical attention if you develop anything that "just does not seem right."
An Introduction to Orap Side EffectsJust like any medicine, Orap® (pimozide) can cause side effects. However, not everyone who takes the drug will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Orap. Your healthcare provider can discuss a more complete list with you.)
Common Side Effects of OrapOrap has been studied extensively in clinical trials. In these studies, one group of people received Orap, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In these studies, the most common Orap side effects in adults included:
- Sedation -- in up to 14 percent of people
- Restlessness -- up to 8 percent
- Loss of muscle control -- up to 8 percent
- Drowsiness -- up to 7 percent
- Dry mouth -- up to 5 percent
- Abnormal behaviors -- up to 5 percent
- Constipation -- up to 4 percent
- Vision problems -- up to 4 percent.
Other common reactions, occurring in 1 percent to 3 percent of people, included:
- Muscle tightness or rigidity
- Erectile dysfunction (impotence)
- Speech problems
- Stooped posture
- Increased appetite
- Changes in handwriting
- Taste changes
- Sensitivity of the eyes to the light.
The most common Orap side effects in clinical trials in children included:
- Drowsiness -- in up to 27.7 percent of children
- Behavior problems -- up to 27.7 percent
- Weakness and lack of energy -- up to 25 percent
- Headache -- up to 22.2 percent
- Increased saliva -- up to 13.8 percent
- Nervousness -- up to 8.3 percent
- Rash -- up to 8.3 percent
- Vision problems -- up to 5.5 percent
- Hyperactivity -- up to 5.5 percent.
Other common problems, occurring in 2.7 percent of children, included:
- Difficulty swallowing
- Muscle pain
- Abnormal dreams
- Abnormal neck movements
Other possible side effects of Orap reported in all clinical trials included:
- Eye swelling
- Chest pain
- Dizziness upon standing
- Increased heart rate
- Nausea and vomiting
- Decreased appetite
- Heartburn or indigestion
- Decreased sex drive
- Changes in weight
- Abnormal body movements
- Skin irritation
- An overactive bladder.