Mysoline is a prescription medicine that can be used alone or in combination with other medications to treat epilepsy. Specifically, it is approved for treating grand mal and partial seizures. The medication is available in the form of a tablet that is usually taken one to three times a day. Although most people tolerate it well, there are possible side effects of the medication, including coordination problems, drowsiness, and spinning sensations (vertigo).
Currently, Mysoline is made by West-ward Pharmaceutical Corp.
How Does Mysoline Work?
In the body, Mysoline is converted into various other chemicals, including phenobarbital. Phenobarbital is a type of barbiturate and can help control seizures by acting as an anticonvulsant. Unlike Mysoline, phenobarbital is considered a controlled substance. This means that there are special rules for prescribing and dispensing phenobarbital (which do not apply to Mysoline). This is one of the main advantages of Mysoline. Some people consider this medication to be a barbiturate, while others do not.
Epilepsy is a brain disorder caused by recurring, brief changes in the brain's electrical system. These changes in brain activity can lead to a seizure (see Epilepsy Symptoms). Mysoline (and phenobarbital) works by decreasing the excitability of the brain cells. This helps to prevent abnormal electrical activity from starting and keeps such activity from spreading to other parts of the brain.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed June 20, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed June 20, 2007.
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