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Certain people who have complex partial seizures or grand mal seizures may be given ethotoin to help prevent abnormal activity from spreading to other parts of the brain. This prescription medicine comes as tablets that are taken four to six times a day after eating. Possible side effects include fatigue, swollen lymph nodes, and vomiting.

What Is Ethotoin?

Ethotoin (Peganone®) is a prescription medication used to treat epilepsy. Specifically, this drug is approved to treat the following conditions:
 
 
Ethotoin is an older medication that is not used much anymore, as it has been largely replaced by similar medications that do not have to be taken so frequently.
 
(Click What Is Ethotoin Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, ethotoin may cause side effects. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well.
 
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Common side effects of ethotoin include but are not limited to:
 
  • Nausea and vomiting (especially if the drug is not taken after meals)
  • Insomnia
  • Fatigue
  • Swollen lymph nodes.
 
(Click Ethotoin Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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