Nervous System Home > Entacapone

When and How to Take This Medication

General considerations for when and how to take entacapone include the following:
  • The medication comes in tablet form. It is taken by mouth along with each dose of carbidopa-levodopa.
  • You can take entacapone with or without food.
  • Make sure to take entacapone at the same times each day to maintain an even level in your blood.
  • For the medication to work properly, it must be taken as prescribed. Entacapone will not work if you stop taking it. Do not stop taking the drug suddenly without first talking to your healthcare provider.

Dosing Information

The dose of entacapone your healthcare provider recommends will vary, depending on a number of factors, including:
  • How often you take carbidopa-levodopa
  • How you respond to entacapone (especially if you develop bothersome side effects)
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Entacapone Dosage for more information.)

Drug Interactions

Entacapone can potentially interact with a number of other medicines (see Drug Interactions With Entacapone).

What If I Take an Overdose of Entacapone?

It is not known what to expect from an overdose with entacapone, although some studies suggest that taking too much may cause the following symptoms:
  • Abdominal pain (stomach pain)
  • Loose stools
  • Breathing problems
  • Loss of coordination
  • Seizures.
If you happen to take too much entacapone, seek immediate medical attention.
(Click Comtan Overdose for more information.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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