Nervous System Home > Dimethyl Fumarate

People who have certain types of multiple sclerosis may benefit from treatment with dimethyl fumarate. This prescription drug is reserved for use in the treatment of relapsing forms of multiple sclerosis. It comes as a capsule that is taken twice daily. The dosage is standard for everyone taking this drug, regardless of your age or weight.


What Is Dimethyl Fumarate?

Dimethyl fumarate (Tecfidera™) is a prescription medication approved to treat people with relapsing forms of multiple sclerosis (MS). In relapsing forms of MS, there are distinct periods when symptoms are worse (known as attacks, relapses, or flare-ups). Dimethyl fumarate can help reduce the number of attacks a person has.
Dimethyl fumarate was known as BG-12 when it was being developed. It is still sometimes referred to as BG-12.
(Click What Is Dimethyl Fumarate Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, dimethyl fumarate can cause side effects. However, not everyone who uses the drug will experience problems. Most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common side effects seen with dimethyl fumarate include but are not limited to:
  • Flushing
  • Abdominal (stomach) pain
  • Diarrhea
  • Nausea.
(Click Dimethyl Fumarate Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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