Precautions and Warnings With Clobazam

• A history of drug or alcohol abuse
• Depression
• Breathing problems
• Any allergies, including to foods, dyes, or preservatives.

• Pregnant or thinking of becoming pregnant
• Breastfeeding.

• Studies suggest that seizure medications may increase the risk for suicide. Make sure to watch for any unusual behaviors or mood changes, and be sure your family and friends know to keep an eye out for such problems.

• Clobazam is a controlled substance, which means it has the potential to be abused. There are special rules and regulations for prescribing and dispensing clobazam. This medicine should be used with caution in people with a history of alcohol or drug abuse.

• Because clobazam can cause physical and psychological dependence, you should not stop taking the drug suddenly without first discussing it with your healthcare provider. He or she can gradually decrease your dosage over several weeks to help wean you off the medication.

• Clobazam can cause severe drowsiness and difficulty breathing, which can be fatal. This risk is increased when clobazam is combined with alcohol, narcotics, or other medications or substances that cause drowsiness and sedation (see Drug Interactions With Clobazam for more information). You should not drive or operate heavy machinery until you know how this drug will affect you.

• Clobazam is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Onfi and Pregnancy).

• Clobazam passes through human breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Onfi and Breastfeeding).