Nervous System Home > Clobazam Side Effects

Contact your healthcare provider if you are taking clobazam and experience depression, suicidal thoughts, or frequent falls. Although these types of problems may be serious, most reactions to this drug tend to be minor and easy to treat. Some of the more common side effects of clobazam include drooling, drowsiness, and upper respiratory tract infections.

An Introduction to Side Effects of Clobazam

Just like any medicine, clobazam (Onfi™) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with clobazam. Your healthcare provider can discuss a more complete list with you.)

Clobazam Side Effects to Report

Some side effects of clobazam are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Depression
  • Anxiety
  • Suicidal thoughts
  • Problems with balance, especially frequent falls (which are especially dangerous in the elderly)
  • Any other mood changes or unusual changes in behavior
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
Stopping clobazam too quickly can cause serious effects, as well. Symptoms of a clobazam withdrawal can include:
  • Seizures
  • Psychotic thoughts or behaviors, including hallucinations
  • Behavioral problems
  • Shakiness
  • Anxiety
  • Insomnia
  • Vague unpleasant feelings.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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