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Common Side Effects

Clobazam has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking clobazam (plus their usual seizure medications) were documented and compared to the side effects that occurred in another group of people taking their usual seizure medications plus a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group taking the placebo.
Because clobazam was added to other seizure medications (not used alone) in clinical studies, the information from these studies probably does not accurately reflect the true incidence of side effects that were specifically caused by clobazam.
In these studies, the most common side effects of clobazam (plus other seizure medications) included:
  • Drowsiness -- in up to 32 percent of people
  • Fever -- up to 17 percent
  • Lethargy -- up to 15 percent
  • Aggression -- up to 14 percent
  • Upper respiratory tract infections (such as the common cold) -- up to 14 percent
  • Drooling -- up to 14 percent
  • Irritability -- up to 11 percent
  • Problems with muscle coordination -- up to 10 percent
  • Constipation -- up to 10 percent.
Other common clobazam side effects, occurring in 5 to 9 percent of people, included:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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