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Levetiracetam Dosing for Partial or Grand Mal Seizures
The recommended starting levetiracetam dose for treating partial seizures or generalized tonic-clonic (grand mal) seizures in adults and adolescents age 16 and older is levetiracetam 500 mg twice daily. Typically, your healthcare provider will slowly increase your levetiracetam dose until your seizures are controlled or you develop bothersome side effects. For this age group, the maximum levetiracetam dose is levetiracetam 3000 mg total per day.
For children age 6 months to 15 years old with partial seizures (or children age 6 years to 15 years old with grand mal seizures), the recommended levetiracetam dose depends on weight. Usually, the starting dose is levetiracetam 10 mg per kg twice daily (about 4.5 mg per pound twice daily). Your child's healthcare provider will slowly increase the dose until an effective dose is reached (or your child develops bothersome side effects).
For infants age 1 month up to 6 months old with partial seizures, the recommended starting dosage also depends on weight and is usually 7 mg per kg twice daily (about 3.2 mg per pound twice daily). The dosage may be increased slowly as necessary.
Some considerations for people taking levetiracetam include the following:
- Levetiracetam comes in tablet and oral liquid form, and is taken by mouth twice daily.
- Levetiracetam also comes in an injectable form for people who cannot take levetiracetam by mouth (such as during hospitalization).
- Levetiracetam can be taken with or without food. If levetiracetam bothers your stomach, try taking it with food.
- If you are taking the oral liquid form (levetiracetam solution), make sure you know exactly how to measure your dose. In general, household spoons are not accurate enough for medication use. Ask your pharmacist about the best way to measure your levetiracetam dose.
- Levetiracetam should be taken at the same times each day to maintain an even level of the drug in your blood.
- If you are unsure about anything related to levetiracetam or your levetiracetam dosage, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without discussing it with your healthcare provider (see Keppra Withdrawal).