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Side Effects of Lacosamide

Common Side Effects

Lacosamide has been thoroughly studied in clinical trials. In these studies, the side effects that occurred in a group of people taking lacosamide (plus their usual seizure medications) were documented and then compared to the side effects that occurred in another group of people taking their usual seizure medications plus a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what lacosamide side effects occurred, how often they appeared, and how they compared to the group taking the placebo.
Because lacosamide was added to other seizure medications (and not used by itself) in clinical studies, the information from these studies probably does not accurately reflect the true incidence of side effects actually caused by lacosamide.
In these studies, the most common side effects of lacosamide (plus other seizure medications) included:
  • Dizziness -- in up to 53 percent of people
  • Nausea -- up to 17 percent
  • Vomiting -- up to 16 percent
  • Double vision -- up to 16 percent
  • Blurred vision -- up to 16 percent
  • Fatigue -- up to 15 percent
  • Coordination problems -- up to 15 percent.
Other common side effects, occurring in 2 to 14 percent of people, included (but were not limited to):
  • A spinning sensation (vertigo)
  • Diarrhea
  • Walking gait changes
  • General weakness
  • Headaches
  • Drowsiness
  • Shakiness (tremors)
  • Involuntary eye movements
  • Balance problems
  • Memory problems.

Other Possible Lacosamide Side Effects

Other lacosamide side effects, for which the exact percentage has not been reported, include (but are not limited to):
  • Anemia
  • Neutropenia (low levels of certain white blood cells)
  • Ringing in the ears (tinnitus)
  • Constipation
  • Indigestion or heartburn
  • Dry mouth
  • Numbness of the mouth
  • Irritability
  • Fever
  • Feeling "drunk"
  • Falling
  • Muscle spasms.
Know the Signs - Concussion Safety

Lacosamide Drug Information

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