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Kemadrin Dosage
In most cases, the recommended starting Kemadrin dosage is 2.5 mg three times daily (after meals). However, this dosage will vary based on several factors, such as the medical condition being treated, how you respond to Kemadrin, other medical conditions you have, and other medications you are taking. If you tolerate Kemadrin well, your healthcare provider may increase your dosage.
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The dose of Kemadrin® (procyclidine hydrochloride) your healthcare provider recommends will vary, depending on a number of factors, including:
- The medical condition being treated
- How you respond to Kemadrin (especially if you develop side effects)
- Other medications you are taking
- Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
For most people, the recommended Kemadrin starting dose is 2.5 mg three times daily (after meals). If you tolerate this dose well, your healthcare provider may increase your dose to Kemadrin 5 mg three times daily (after meals) or even four times daily (after meals and at bedtime).
For treating extrapyramidal symptoms (EPS) due to antipsychotic medications, the recommended starting Kemadrin dosage is 2.5 mg three times daily (after meals). Your healthcare provider will increase your dose as necessary. Most people do well with a dose of 10 mg to 20 mg total per day.
There are no specific recommendations for the dosing of Kemadrin to treat excessive drooling due to Parkinson's disease or antipsychotic medications. It is reasonable to start with the standard dosing recommendations for treating Parkinson's disease or EPS (2.5 mg three times a day).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



