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Precautions and Warnings With Fingolimod

Who Should Not Take Fingolimod?

You should not take fingolimod if you:
  • Have had a heart attack, stroke, transient ischemic attack (TIA or "mini-stroke"), or unstable angina (a type of chest pain) in the past six months.
  • Had moderate-to-severe heart failure (Class III or IV heart failure) or worsening heart failure that required you to be hospitalized in the past six months.
  • Have certain types of heart rhythm problems (arrhythmias), such as second- or third-degree heart block or sick sinus syndrome, and do not have a functioning pacemaker.
  • Had prolonged QT (a change in the heart's normal rhythm) on an ECG just prior to starting fingolimod.
  • Are taking Class Ia or III arrhythmia medications (see Drug Interactions With Fingolimod).
  • Are allergic to Gilenya, fingolimod, or any of the inactive components used to make the medication. Your healthcare provider or pharmacist has a list of the inactive ingredients.

Final Thoughts

There are a number of situations in which fingolimod should not be taken, along with several safety concerns people should be aware of before beginning treatment. However, it is possible that not all of these issues were discussed in this article. Therefore, you should talk with your healthcare provider about the specific warnings and precautions with fingolimod that may apply to you.
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